{"id":2693,"date":"2019-11-26T09:15:21","date_gmt":"2019-11-26T09:15:21","guid":{"rendered":"https:\/\/biology-and-environment.haifa.ac.il\/?page_id=2693"},"modified":"2022-09-28T06:04:11","modified_gmt":"2022-09-28T06:04:11","slug":"dr-avi-bar-massada-4","status":"publish","type":"page","link":"https:\/\/biology-and-environment.haifa.ac.il\/?page_id=2693","title":{"rendered":"\u05e4\u05e8\u05d5\u05e4' \u05d0\u05dc\u05d4 \u05e4\u05d9\u05e7"},"content":{"rendered":"\t\t
\n\t\t\t\t\t\t
\n\t\t\t\t\t\t
\n\t\t\t\t\t
\n\t\t\t
\n\t\t\t\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t

\u05e4\u05e8\u05d5\u05e4' \u05d0\u05dc\u05d4 \u05e4\u05d9\u05e7<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
\n\t\t\t\t\t\t
\n\t\t\t\t\t
\n\t\t\t
\n\t\t\t\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t

\u05e4\u05e8\u05d5\u05e4\u05e1\u05d5\u05e8 \u05d7\u05d1\u05e8<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
\n\t\t\t\t\t\t
\n\t\t\t\t\t
\n\t\t\t
\n\t\t\t\t\t\t
\n\t\t\t\t\t\t
\n\t\t\t\t\t
\n\t\t\t
\n\t\t\t\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\"\"\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t
\n\t\t\t
\n\t\t\t\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t\t\t\t\t

\u200b\u05d4\u05de\u05d7\u05e7\u05e8 \u05e9\u05dc\u05e0\u05d5 \u05de\u05ea\u05de\u05e7\u05d3 \u05d1\u05d4\u05d1\u05e0\u05ea \u05de\u05e0\u05d2\u05e0\u05d5\u05e0\u05d9\u05dd \u05d1\u05e1\u05d9\u05e1\u05d9\u05d9\u05dd \u05d4\u05d3\u05e8\u05d5\u05e9\u05d9\u05dd \u05dc\u05e9\u05de\u05d9\u05e8\u05d4 \u05e2\u05dc \u05de\u05d0\u05d6\u05df \u05d4\u05d7\u05dc\u05d1\u05d5\u05e0\u05d9\u05dd \u05d1\u05ea\u05d0 \u05d1\u05de\u05e6\u05d1\u05d9 \u05e2\u05e7\u05d4 \u05e1\u05d1\u05d9\u05d1\u05ea\u05d9\u05ea \u05db\u05de\u05d5 \u05e7\u05e8\u05d9\u05e0\u05d4 \u05d0\u05d5 \u05e0\u05d6\u05e7\u05d9 \u05d7\u05de\u05e6\u05d5\u05df. \u05e4\u05d2\u05de\u05d9\u05dd \u05d1\u05ea\u05d2\u05d5\u05d1\u05d4 \u05d4\u05ea\u05d0\u05d9\u05ea \u05dc\u05e2\u05e7\u05d5\u05ea \u05d0\u05dc\u05d4 \u05e2\u05dc\u05d5\u05dc\u05d9\u05dd \u05dc\u05d2\u05e8\u05d5\u05dd \u05dc\u05e9\u05d9\u05d1\u05d5\u05e9 \u05d1\u05d1\u05d9\u05d8\u05d5\u05d9 \u05e9\u05dc \u05d7\u05dc\u05d1\u05d5\u05e0\u05d9 \u05de\u05e4\u05ea\u05d7 \u05d1\u05ea\u05d0\u05d9 \u05d4\u05d2\u05d5\u05e3 \u05d5\u05dc\u05db\u05df \u05dc\u05d2\u05e8\u05d5\u05dd \u05dc\u05de\u05d7\u05dc\u05d5\u05ea \u05db\u05de\u05d5 \u05e1\u05d5\u05d2\u05d9 \u05e1\u05e8\u05d8\u05df \u05e9\u05d5\u05e0\u05d9\u05dd, \u05dc\u05de\u05d7\u05dc\u05d5\u05ea \u05e0\u05d5\u05d9\u05e8\u05d5\u05d3\u05d2\u05e0\u05e8\u05d8\u05d9\u05d1\u05d9\u05d5\u05ea \u05db\u05de\u05d5 \u05d0\u05dc\u05e6\u05d4\u05d9\u05d9\u05de\u05e8 \u05d5\u05e4\u05e8\u05e7\u05d9\u05e0\u05e1\u05d5\u05df \u05d0\u05d5 \u05dc\u05d4\u05d6\u05d3\u05e7\u05e0\u05d5\u05ea. \u05de\u05d5\u05d3\u05dc \u05d4\u05de\u05d7\u05e7\u05e8 \u05d4\u05e2\u05d9\u05e7\u05e8\u05d9 \u05d1\u05de\u05e2\u05d1\u05d3\u05d4 \u05e9\u05dc\u05e0\u05d5 \u05d4\u05d5\u05d0 \u05e9\u05de\u05e8 \u05de\u05e0\u05e5. \u05d7\u05d3-\u05ea\u05d0 \u05d6\u05d4 \u05d4\u05d9\u05e0\u05d5 \u05d4\u05de\u05d5\u05d3\u05dc \u05d4\u05d0\u05d0\u05d5\u05e7\u05e8\u05d9\u05d5\u05d8\u05d9 \u05d4\u05e4\u05e9\u05d5\u05d8 \u05d1\u05d9\u05d5\u05ea\u05e8 \u05e9\u05e0\u05d9\u05ea\u05df \u05dc\u05d3\u05de\u05d5\u05ea \u05d1\u05d5 \u05de\u05d7\u05dc\u05d5\u05ea \u05e9\u05dc \u05d4\u05d0\u05d3\u05dd \u05d5\u05d4\u05e1\u05d1\u05d9\u05d1\u05d4. \u05d1\u05e9\u05dc \u05e4\u05e9\u05d8\u05d5\u05ea\u05d5 \u05d4\u05de\u05d7\u05e7\u05e8 \u05d1\u05d5 \u05d0\u05d9\u05e0\u05d5 \u05de\u05d4\u05d5\u05d5\u05d4 \u05d1\u05e2\u05d9\u05d4 \u05d0\u05ea\u05d9\u05ea. \u05dc\u05d0\u05d7\u05e8\u05d5\u05e0\u05d4 \u05d4\u05d5\u05e1\u05e4\u05e0\u05d5 \u05d2\u05dd \u05ea\u05e8\u05d1\u05d9\u05d5\u05ea \u05ea\u05d0\u05d9 \u05d9\u05d5\u05e0\u05e7\u05d9\u05dd. \u05de\u05d5\u05d6\u05de\u05e0\u05d9\u05dd \u05dc\u05d1\u05e7\u05e8 \u05d1\u05de\u05e2\u05d1\u05d3\u05d4 \u05e9\u05dc\u05e0\u05d5 \u05d5\u05dc\u05e9\u05de\u05d5\u05e2 \u05e2\u05d5\u05d3. \u200b<\/p>

\u05d4\u05e9\u05db\u05dc\u05d4 \u05d0\u05e7\u05d3\u05de\u05d9\u05ea<\/u><\/b><\/p>

\u05ea\u05d5\u05d0\u05e8 \u05e8\u05d0\u05e9\u05d5\u05df (.B.Sc): \u05d1\u05d9\u05d5\u05dc\u05d5\u05d2\u05d9\u05d4 \u05d5\u05e1\u05d1\u05d9\u05d1\u05d4 – \u05d0\u05d5\u05e0\u05d9\u05d1\u05e8\u05e1\u05d9\u05d8\u05ea \u05d7\u05d9\u05e4\u05d4<\/p>

\u05ea\u05d5\u05d0\u05e8 \u05e9\u05e0\u05d9 (.M.Sc): \u05e0\u05d5\u05d9\u05e8\u05d5\u05d1\u05d9\u05d5\u05db\u05d9\u05de\u05d9\u05d4 – \u05d0\u05d5\u05e0\u05d9\u05d1\u05e8\u05e1\u05d9\u05d8\u05ea \u05ea\u05dc \u05d0\u05d1\u05d9\u05d1<\/span><\/p>

\u05ea\u05d5\u05d0\u05e8 \u05e9\u05dc\u05d9\u05e9\u05d9 (.Ph.D): \u05d1\u05d9\u05d5\u05dc\u05d5\u05d2\u05d9\u05d4 – \u05d4\u05d8\u05db\u05e0\u05d9\u05d5\u05df<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

\n\t\t\t\t\t\t
\n\t\t\t\t\t
\n\t\t\t
\n\t\t\t\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t\t\t\t\t

\u05d0\u05ea\u05e8 \u05d4\u05d1\u05d9\u05ea \u05e9\u05dc \u05d4\u05de\u05e2\u05d1\u05d3\u05d4<\/a><\/strong><\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

\n\t\t\t\t\t\t
\n\t\t\t\t\t
\n\t\t\t
\n\t\t\t\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t

\u05e4\u05e8\u05e1\u05d5\u05de\u05d9\u05dd \u05de\u05d3\u05e2\u05d9\u05d9\u05dd \u05e0\u05d1\u05d7\u05e8\u05d9\u05dd<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
\n\t\t\t\t\t\t
\n\t\t\t\t\t
\n\t\t\t
\n\t\t\t\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t\t\t\t\t

Yu, Z., Kleifeld, O., Lande-Atir A., Bsoul, M., Kleiman, M., Krutauz, D., Book, A., Vierstra, A.D., Hofmann, K., Glickman, M.H.+ and Pick, E. (2011) Dual function of Rpn5 in two PCI complexes, the 26S proteasome and the COP9 signalosome. Molecular Biology of the Cell 22: 911-20.<\/p>\n

Pick, E., Golan, A., Zimbler J.Z., Guo, L., Sharaby, Y., Tsuge, T., Hofmann, K., Wei, N. (2012) The Minimal Deneddylase Core of the Cop9 Signalosome Excludes the Csn6 MPN- Domain. PLoS One. 7:e43980. doi: 10.1371\/journal.pone.0043980.<\/p>\n

Serino, G. and Pick, E. (2013) Duplication and familial promiscuity within the proteasome lid and COP9 signalosome kin complexes. Plant Science. DOI: 10.1016\/j.plantsci.2012.12.018.<\/p>\n

Mahon, C.S., Krogan, N.J., Craig, C.S., and Pick, E., (2014) Cullin E3 Ligases and Their Rewiring by Viral Factors. Biomolecules 4:897-930.<\/p>\n

Bramasole, L., Sinha, A., Gurevich, S., Radzinski, M., Klein, Y., Panat, N., Gefen, E., Rinaldi, T., Jimenez-Morales, D., Johnson, J., Krogan, NJ., Reis, N., Reichmann, D., Glickman, MH., Pick, E. (2019) Proteasome lid bridges mitochondrial stress with Cdc53\/Cullin1 NEDDylation status. Redox Biology. 20:533-543.<\/p>\n

Bramasole, L., Sinha, A., Harshuk, D., Cirigliano, A., Gurevich, S., Yu, Z., Carmeli, RL., Glickman, MH., Rinaldi, T., Pick, E. (2019) The proteasome lid triggers COP9 signalosome activity during the transition of Saccharomyces cerevisiae cells into quiescence. Biomolecules. (9). pii: E449.<\/p>\n

\n<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

\n\t\t\t\t\t\t
\n\t\t\t\t\t
\n\t\t\t
\n\t\t\t\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t

\u05d4\u05d5\u05e8\u05d0\u05d4<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
\n\t\t\t\t\t\t
\n\t\t\t\t\t
\n\t\t\t
\n\t\t\t\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t\t\t\t\t

\u05d1\u05d9\u05d5\u05dc\u05d5\u05d2\u05d9\u05d4 \u05e9\u05dc \u05d4\u05ea\u05d0, \u05d1\u05d9\u05d5\u05dc\u05d5\u05d2\u05d9\u05d4 \u05de\u05d5\u05dc\u05e7\u05d5\u05dc\u05e8\u05d9\u05ea<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

\u05e4\u05e8\u05d5\u05e4' \u05d0\u05dc\u05d4 \u05e4\u05d9\u05e7 \u05e4\u05e8\u05d5\u05e4\u05e1\u05d5\u05e8 \u05d7\u05d1\u05e8 \u200b\u05d4\u05de\u05d7\u05e7\u05e8 \u05e9\u05dc\u05e0\u05d5 \u05de\u05ea\u05de\u05e7\u05d3 \u05d1\u05d4\u05d1\u05e0\u05ea \u05de\u05e0\u05d2\u05e0\u05d5\u05e0\u05d9\u05dd \u05d1\u05e1\u05d9\u05e1\u05d9\u05d9\u05dd \u05d4\u05d3\u05e8\u05d5\u05e9\u05d9\u05dd \u05dc\u05e9\u05de\u05d9\u05e8\u05d4 \u05e2\u05dc \u05de\u05d0\u05d6\u05df \u05d4\u05d7\u05dc\u05d1\u05d5\u05e0\u05d9\u05dd \u05d1\u05ea\u05d0 \u05d1\u05de\u05e6\u05d1\u05d9 \u05e2\u05e7\u05d4 \u05e1\u05d1\u05d9\u05d1\u05ea\u05d9\u05ea \u05db\u05de\u05d5 \u05e7\u05e8\u05d9\u05e0\u05d4 \u05d0\u05d5 \u05e0\u05d6\u05e7\u05d9 \u05d7\u05de\u05e6\u05d5\u05df. \u05e4\u05d2\u05de\u05d9\u05dd \u05d1\u05ea\u05d2\u05d5\u05d1\u05d4 \u05d4\u05ea\u05d0\u05d9\u05ea \u05dc\u05e2\u05e7\u05d5\u05ea \u05d0\u05dc\u05d4 \u05e2\u05dc\u05d5\u05dc\u05d9\u05dd \u05dc\u05d2\u05e8\u05d5\u05dd \u05dc\u05e9\u05d9\u05d1\u05d5\u05e9 \u05d1\u05d1\u05d9\u05d8\u05d5\u05d9 \u05e9\u05dc \u05d7\u05dc\u05d1\u05d5\u05e0\u05d9 \u05de\u05e4\u05ea\u05d7 \u05d1\u05ea\u05d0\u05d9 \u05d4\u05d2\u05d5\u05e3 \u05d5\u05dc\u05db\u05df \u05dc\u05d2\u05e8\u05d5\u05dd \u05dc\u05de\u05d7\u05dc\u05d5\u05ea \u05db\u05de\u05d5 \u05e1\u05d5\u05d2\u05d9 \u05e1\u05e8\u05d8\u05df \u05e9\u05d5\u05e0\u05d9\u05dd, \u05dc\u05de\u05d7\u05dc\u05d5\u05ea \u05e0\u05d5\u05d9\u05e8\u05d5\u05d3\u05d2\u05e0\u05e8\u05d8\u05d9\u05d1\u05d9\u05d5\u05ea \u05db\u05de\u05d5 \u05d0\u05dc\u05e6\u05d4\u05d9\u05d9\u05de\u05e8 \u05d5\u05e4\u05e8\u05e7\u05d9\u05e0\u05e1\u05d5\u05df \u05d0\u05d5 \u05dc\u05d4\u05d6\u05d3\u05e7\u05e0\u05d5\u05ea. \u05de\u05d5\u05d3\u05dc \u05d4\u05de\u05d7\u05e7\u05e8 […]<\/p>\n","protected":false},"author":3,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"ocean_front_end_style_editor":"no","ocean_post_layout":"","ocean_both_sidebars_style":"","ocean_both_sidebars_content_width":0,"ocean_both_sidebars_sidebars_width":0,"ocean_sidebar":"0","ocean_second_sidebar":"0","ocean_disable_margins":"enable","ocean_add_body_class":"","ocean_shortcode_before_top_bar":"","ocean_shortcode_after_top_bar":"","ocean_shortcode_before_header":"","ocean_shortcode_after_header":"","ocean_has_shortcode":"","ocean_shortcode_after_title":"","ocean_shortcode_before_footer_widgets":"","ocean_shortcode_after_footer_widgets":"","ocean_shortcode_before_footer_bottom":"","ocean_shortcode_after_footer_bottom":"","ocean_display_top_bar":"default","ocean_display_header":"default","ocean_header_style":"","ocean_center_header_left_menu":"0","ocean_custom_header_template":"0","ocean_custom_logo":0,"ocean_custom_retina_logo":0,"ocean_custom_logo_max_width":0,"ocean_custom_logo_tablet_max_width":0,"ocean_custom_logo_mobile_max_width":0,"ocean_custom_logo_max_height":0,"ocean_custom_logo_tablet_max_height":0,"ocean_custom_logo_mobile_max_height":0,"ocean_header_custom_menu":"0","ocean_menu_typo_font_family":"0","ocean_menu_typo_font_subset":"","ocean_menu_typo_font_size":0,"ocean_menu_typo_font_size_tablet":0,"ocean_menu_typo_font_size_mobile":0,"ocean_menu_typo_font_size_unit":"px","ocean_menu_typo_font_weight":"","ocean_menu_typo_font_weight_tablet":"","ocean_menu_typo_font_weight_mobile":"","ocean_menu_typo_transform":"","ocean_menu_typo_transform_tablet":"","ocean_menu_typo_transform_mobile":"","ocean_menu_typo_line_height":0,"ocean_menu_typo_line_height_tablet":0,"ocean_menu_typo_line_height_mobile":0,"ocean_menu_typo_line_height_unit":"","ocean_menu_typo_spacing":0,"ocean_menu_typo_spacing_tablet":0,"ocean_menu_typo_spacing_mobile":0,"ocean_menu_typo_spacing_unit":"","ocean_menu_link_color":"","ocean_menu_link_color_hover":"","ocean_menu_link_color_active":"","ocean_menu_link_background":"","ocean_menu_link_hover_background":"","ocean_menu_link_active_background":"","ocean_menu_social_links_bg":"","ocean_menu_social_hover_links_bg":"","ocean_menu_social_links_color":"","ocean_menu_social_hover_links_color":"","ocean_disable_title":"default","ocean_disable_heading":"default","ocean_post_title":"","ocean_post_subheading":"","ocean_post_title_style":"","ocean_post_title_background_color":"","ocean_post_title_background":0,"ocean_post_title_bg_image_position":"","ocean_post_title_bg_image_attachment":"","ocean_post_title_bg_image_repeat":"","ocean_post_title_bg_image_size":"","ocean_post_title_height":0,"ocean_post_title_bg_overlay":0.5,"ocean_post_title_bg_overlay_color":"","ocean_disable_breadcrumbs":"default","ocean_breadcrumbs_color":"","ocean_breadcrumbs_separator_color":"","ocean_breadcrumbs_links_color":"","ocean_breadcrumbs_links_hover_color":"","ocean_display_footer_widgets":"default","ocean_display_footer_bottom":"default","ocean_custom_footer_template":"0","footnotes":""},"class_list":["post-2693","page","type-page","status-publish","hentry","entry"],"_links":{"self":[{"href":"https:\/\/biology-and-environment.haifa.ac.il\/index.php?rest_route=\/wp\/v2\/pages\/2693","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/biology-and-environment.haifa.ac.il\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/biology-and-environment.haifa.ac.il\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/biology-and-environment.haifa.ac.il\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/biology-and-environment.haifa.ac.il\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2693"}],"version-history":[{"count":13,"href":"https:\/\/biology-and-environment.haifa.ac.il\/index.php?rest_route=\/wp\/v2\/pages\/2693\/revisions"}],"predecessor-version":[{"id":3322,"href":"https:\/\/biology-and-environment.haifa.ac.il\/index.php?rest_route=\/wp\/v2\/pages\/2693\/revisions\/3322"}],"wp:attachment":[{"href":"https:\/\/biology-and-environment.haifa.ac.il\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2693"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}